姓　　名： 劉寶 性別： 男

出生年月： 1962-11-26 工作單位： 東北師范大學

所在院系： 生命科學學院 職稱： 教授

行政職務： 招生專業： 071001植物學

研究領域： 植物遺傳學基礎和應用 是否兼職： 否

指導博士生總數： 指導碩士生總數：

目前博士生數： 目前碩士生數：

個人簡介

【個人情況綜述】 　　1992年畢業于南京農業大學獲博士學位；1995-1997，在以色列Weizmann Institute of Science植物科學系從事博士后研究；2000-2001，在美國Iowa State University生態與進化系做訪問學者。 　　主要從事植物基因組進化和利用遠緣雜交及生物技術進行作物遺傳改良的研究。 在植物異源多倍體基因組進化和利用野生稻（菰, Zizania latifolia）改良水稻等方面取得多項成果。 發表研究論文60余篇，其中50余篇發表在本領域國際雜志（SCI）上。研究成果受到國際權威的認可和好評，多篇論文已被國際同行廣泛引用。據不完全統計，從1998年至今被SCI雜志他人引用超過500次， 包括被Nature Genetics, Nature Biotechnology, The EMBO Journal, , PNAS, Trends in Genetics, The Plant Cell等國際權威雜志的多次引用和評述。自1999年以來分別應邀為Genetics, Plant Physiology, Plant Molecular Biology, Theoretical and Applied Genetics, Genome, Genetica 等多家本領域國際雜志評審論文。 2次被國際雜志Current Genomics 和Molecular Phylogenetics and Evolution 約稿撰寫綜述。 　　應用研究方面作為主要合作者，通過生物技術與傳統育種相結合，培育出6個作物新品種，并參加了其推廣工作。其中水稻新品種“通35號”連續多年占吉林省水稻種植總面積的50％以上，已累計增產稻谷超過30億公斤。應用成果獲得5項省級科技獎勵。 　　至今已負責并完成多項國家和地方政府支持的基礎課題的研究工作。目前正在承擔 “國家杰出青年科學基金”、“國家自然科學基金重點項目”和國家科技部“973項目”（子課題）等課題的研究工作。 　　【學習工作簡歷】 　　主要學習簡歷 　　1981-1985，吉林農業大學農學系，本科，獲學士學位。 　　1985-1988，吉林農業大學農學系，研究生，獲碩士學位。 　　1989-1992，南京農業大學細胞遺傳研究所，研究生，獲博士學位。 　　1992-1994，東北師范大學遺傳與細胞研究所，博士后研究人員。 　　1995-1997，以色列Weizmann Institute of Science植物科學系，博士后研究人員。 　　2000-2001，美國Iowa State University, 生態與進化系，訪問學者。 　　主要工作簡歷 　　1992-1994，東北師范大學遺傳與細胞研究所，博士后研究人員。 　　1998－2003，東北師范大學遺傳與細胞研究所，教授、博士生導師。 　　2003-至今，東北師范大學植物分子表觀遺傳學實驗室，主任、教授、博士生導師。 　　【社會學術兼職】 　　1．“國家基金委”生命學部二審專家 　　2．“全國科技名詞審定委員會” 委員 　　3．“吉林省遺傳學會” 理事

獲得獎項

應用研究成果獲得5項省級科技獎勵。

著作及論文

發表的主要論文 (*為通訊作者)： 　　1.Yu Chen, Likun Long, Xiuyun Lin, Wanli Guo and Bao Liu*. (2006) Isolation and characterization of a set of disease resistance gene analogs (RGAs) from wild rice, Zizania latifolia Griseb.I. introgression, copy number liability, sequence change and DNA methylation alteration in several rice-Zizania introgression lines. Genome (in press). 　　2.Wanli Guo, Yidan Li, Lei Gong, Fengxia Li, Yingshan Dong & Bao Liu*. (2006). Efficient micropropagation of Robinia ambigua var. idahoensis (Idaho Locust) and detection of genomic variation by ISSR markers. Plant Cell, Tissue and Organ Culture (in press). 　　3.W. L. Guo,　L. Gong,　Z. F. Ding,　Y. D. Li,　F. X. Li,　Y. P. Zhao and　B. Liu*. (2006) Genomic instability in phenotypically normal regenerants of medicinal plant Codonopsis lanceolata Benth. et Hook. f., as revealed by ISSR and RAPD markers. Plant Cell Reports (in press). 　　4.Long L, Lin X, Zhai J, Kou H, Yang W, Liu B*. (2006) Heritable alteration in DNA methylation pattern occurred specifically at mobile elements in rice plants following hydrostatic pressurization. 　　Biochem Biophys Res Commun. 340: 369-376. 　　5.Yong-Ming Wang, Zhen-Ying Dong, Zhong-Juan Zhang, Xiu-Yun Lin, Ye Shen, Daowei Zhou and　 Bao Liu*. (2005) Extensive de novo Genomic Variation in Rice Induced by Introgression from Wild Rice (Zizania latifolia Griseb.) Genetics, 170: 1945-1956. 　　6.Fangpu Han, George Fedak, Wanli Guo, and Bao Liu*. (2005) Rapid And Repeatable Elimination of a Parental Genome-Specific DNA Repeat (pGc1R-1a) in Newly Synthesized Wheat Allopolyploids Genetics, 170: 11239-1245. 　　7.Xiaohui Shan, Zhenlan Liu, Zhenying Dong, Yongming Wang, Yu Chen, Xiuyun Lin, Likun Long, Fangpu Han, Yingshan Dong and Bao Liu*. (2005) Mobilization of the Active MITE Transposons mPing and Pong in Rice by Introgression from Wild Rice (Zizania latifolia Griseb.) Molecular Biology and Evolution 22: 976-990. 　　8.Y. Z. Dong, Z. L. Liu, X. H. Shan, T. Qiu, M. Y. He and Bao Liu*. (2005) Allopolyploidy in Wheat Induces Rapid and Heritable Alterations in DNA Methylation Patterns of Cellular Genes and Mobile Elements. Genetike, 41: 1089-1095. 　　9.Ye Shen, Xiuyun Lin, Xiaohui Shan, Chunjing Lin, Fangpu Han, Jinsong Pang and Bao Liu*. (2005) Extensive Genomic Rearrangement in Endogenous Long Terminal Repeat (LTR) Retrotransposons of Rice Lines Introgressed by Wild Rice, Zizania Latifolia Griseb. Journal of Integrative Plant Biology, 47: 998-1008 　　10.Fangpu Han, Bao Liu, George Fedakand Zhaohui Liu. (2004) Genomic constitution and variation in five partial amphiploids of wheat-Thinopyrum intermedium as revealed by GISH, multicolor GISH and seed storage protein analysis. Theoretical and Applied Genetics, 109: 1070-1076. 　　11.Zhenlan Liu, Yongming Wang, Ye Shen, Wanli Guo, Shui Hao, and Bao Liu*. (2004) Extensive alterations in DNA methylation and transcription in rice caused by introgression from Zizania latifolia Plant Molecular Biology, 54: 571-582. 　　12.Z.L. Liu, F.P. Han, M. Tan, X.H. Shan, Y.Z. Dong, X.Z. Wang, G. Fedak, S. Hao, Bao Liu*. (2004) Activation of a rice endogenous retrotransposon Tos17 in tissue culture is accompanied by cytosine demethylation, and causes heritable alteration in methylation pattern of flanking genomic regions. Theoretical and Applied Genetics, 109: 200-209. 　　13.Dong YS, Zhao LM, Liu Bao, Wang ZW, Jin ZQ, Sun H. (2004) The genetic diversity of cultivated soybean grown in China. Theoretical and Applied Genetics 108: 931-936. 　　14.Wang Y, Lin X, Dong B, Wang Y, Liu B. 2004. DNA methylation polymorphism in a set of elite rice cultivars and its possible contribution to inter-cultivar differential gene expression.　Cell Mol Biol Lett. 9: 543-556. 　　15.Yingshan Dong, Xiuling Bu, Yushi Luan, Mengyuan He and Bao Liu*. (2004) Molecular characterization of a cryptic wheat- Thinopyrum intermedium translocation line: evidence for genomic instability in nascent allopolyploid and aneuploid lines. Genetics and Molecular Biology, 27: 237-241. 　　16.Bao Liu & Jonathan F. Wendel. (2003) Epigenetic phenomena and genome evolution in allopolyploid plants. Molecular Phylogenetics & Evolution 29: 365-379. 　　17.Bao Liu, G. Segal, J. K. Rong and M. Feldman. (2003) Characterization of a chromosome-specific sequence in genome B of common wheat implies its origin from Aegilops searsii. Plant Systmatics & Evolution 241: 55-66. 　　18.F. P. Han, G. Fedak, T. Quellet and Bao Liu. (2003) Rapid genomic changes in interspecific and intergeneric hybrids and allopolyploids of Triticeae. Genome 46：716-723. 　　19.David S. Senchina1, Ines Alvarez1, Richard C. Cronn, Bao Liu, Junkang Rong, Richard D. Noyes, Andrew H. Paterson, Rod A. Wing, Thea A. Wilkins, and Jonathan F. Wendel. (2003) Rate variation among nuclear genes and the age of polyploidy in Gossypium. Molecular Biology & Evolution 20: 633-643. 　　20.Bao Liu & Jonathan F. Wendel. (2002) Non-Mendelian phenomena in polyploid genome evolution. Current Genomics 3: 489-506. 　　21. Jonathan F. Wendel, Richard C. Cronn, Ines Alvarez, Bao Liu, Randall L. Small and David S. Senchina. (2002) Intron Size and Genome Size in Plants. Molecular Biology & Evolution 19: 2346–2352. 　　22.Bao Liu, CL Brubaker, G Mergeai, RC Cronn & JF Wendel. (2001) Polyploid formation in cotton is not accompanied by rapid genomic changes. Genome 44: 321-330. 　　23.Bao Liu & Jonathan F. Wendel. 2001. Inter-simple sequence repeat (ISSR) polymorphisms as a genetic marker system in cotton. Molecular Ecology Notes 3: 205-208. 　　24.Bao Liu*, Zhenlan Liu, Yuzhu Dong, Jihong Zhao, Baiqu Huang & Mengyuan He. 2001. Cytosine methylation changes in rice centromeric and telomeric sequences induced by foreign DNA introgression. Biologia Plantarum 44: 203-206. 　　25.Bao Liu*, Yushi Luan, Fangpu Han, Wanquan Ji & Mengyuan He. 2001. Cell culture induced introgression of Thinopyrum intermedium chromatin into common wheat. Plant Cell, Tissue & Organ Culture 65: 9-13. 　　26.Bao Liu & Jonathan F. Wendel. (2000) Retrotransposon activation followed by rapid repression in introgressed rice plants. Genome 43: 874-880. 　　27.Ueng PP, A Hang, H Tsang, JM Vega, L Wang, CS Burton, FT He & Bao Liu. (2000) Molecular analyses of a repetitive DNA sequence in wheat (Triticum aestivum L.). Genome 43: 556-563. 　　28.Bao Liu*, ZL Liu and XW Li. (1999) Production of a highly asymmetric somatic hybrid between rice and Zizania latifolia: evidence for inter-genomic exchange. Theoretical and Applied Genetics 98: 1099-1103 . 　　29.Bao Liu, Hengmao Piao, Fenshan Zhao, Jihong Zhao, Zhenlan Liu & Baiqu Huang. (1999) DNA methylation changes in rice induced by Zizania latifolia (Griseb.) DNA introgression. Hereditas 131: 75-78. 　　30.Bao Liu, JM Vega, M Feldman. (1998) Rapid genomic changes in newly synthesized amphiploids of Triticum and Aegilops. II. changes in low-copy coding DNA sequences. Genome 41: 535-542. 　　31.Bao Liu, JM Vega, G Segal, S Abbo, M Rodova, M Feldman. (1998) Rapid genomic changes in newly synthesized amphiploids of Triticum and Aegilops. I. changes in low-copy noncoding DNA sequences. Genome 41: 272-277. 　　32.Bao Liu, G Segal, JM Vega, M Feldman & S Abbo. (1997) Isolation and characterization of chromosome-specific DNA sequences from a chromosome arm-specific library of common wheat. The Plant Journal 11: 959-965. 　　33.Moshe Feldman, Bao Liu, Gregorio Segal, Shahal Abbo and June M. Vega. (1997) Rapid elimination of low-copy DNA sequences in polyploid wheat: a possible mechanism for differentiation of homoeologous chromosomes. Genetics 147: 1381-1387. 　　34.Segal G, Bao Liu, J.M Vega, S Abbo & M Feldman. (1997) Identification of a chromosome-specific probe that maps within the Ph1 deletion in common and durum wheat. Theoretical and Applied Genetics 94: 968-970. 　　35.Tao Wenjing, Liu Bao* & Xing Miao. (1997) Estabilishing japonica rice suspensions retaining a high regeneration potential after 14 months of culture. Plant Cell, Tissue and Organ Culture 47: 213-216. 　　專利等實用成果： 　　負責或參加的項目成果有近10項通過省級或省級以上鑒定。

承擔項目

（在研項目） 　　（1） 高等植物遠緣雜交誘導的表觀遺傳變異及其在物種進化和新種形成中的可能作用“國家自然科學基金” 重點項目， 2005－2008，負責。 　　（2） 水稻重要農藝性狀的比較基因組研究（編號：2005CB120805）。2006－2010，參加人。 　　（3） 大豆抗食心蟲、高蛋白、高油、抗蚜蟲分子標記及新品種選育。“科技部863計劃” 2004－2006，負責（第二位）。 　　（4） 菰DNA漸滲誘導水稻表觀遺傳變異及其與表型變異的關系。“國家自然科學基金”， 2004.1－2006.12，負責。 　　（5） 高等植物異源多倍體物種形成和基因組進化的機制和規律研究 “國家杰出青年科學基金”,　2003.1－2006.12， 負責 　　（6） 菰DNA漸滲誘導水稻遺傳變異的機理研究“吉林省杰出青年科學研究計劃”（2002-2005），負責