華南理工大學大學輕工與食品學院導師:姜建國

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華南理工大學大學輕工與食品學院導師:姜建國

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華南理工大學大學輕工與食品學院導師:姜建國 正文


  姓名:姜建國  性別:男  職稱:教授  
  學院:輕工與食品學院  最后學歷:博士
  主要研究方向:藻類次生代謝工程;中藥天然產物化學工程

  一、簡介
  姜建國,教授,博士生導師。中國微生物學會分子微生物學與生物工程專業委員會委員,美國食品學會會員,本校“食品化學與生物技術”團隊學術負責人,實驗室主任。國際著名期刊Mini Reviews in Medicinal Chemistry 特約編輯。1982-1986,華中師范大學,學士;1986-1989,武漢大學,碩士;1992-1995,中科院水生所(武漢),博士;1995-1997,華南理工大學,博士后。1997至今,華南理工大學食品學院,生物科學與工程學院。
  
  二、研究方向
  在食品學院與生物學院招收碩士生,在食品學院招收博士生。主要涉及以下兩個方向:
  
  1、藻類與微生物次生代謝工程
  該方向適合生物化學與分子生物學方向考生。主要從事藻類類胡蘿卜素次生代謝途徑的分子克隆、代謝途徑的分子構建、代謝調控的分子機理。
  
  2、中藥與天然產物化學與工程
  該方向適合食品專業和藥物化學專業的考生。主要從事藥食同源品種資源天然產物化學與活性的生物模型研究。
  
  三、主要業績
  主持過4項國家自然科學基金,1項國家科技支撐子課題(項目聯系人),3項廣東省基金,3項省科技攻關項目,1項廣州市科技攻關重點項目等。5項發明專利,專著一部,發表學術論文100多篇,其中SCI論文近60篇(截止2011年9月)。

  在國際上率先開展了杜氏藻類胡蘿卜素次生代謝途徑的分子克隆與代謝調控研究,在次級代謝關鍵酶基因的克隆與表達,關鍵酶基因啟動子的克隆與功能驗證,啟動子鹽和光代謝調控元件,杜氏藻類胡蘿卜素代謝途徑的外源表達與基因工程菌的培育,鹽脅迫與GPDH表達的相關性,鹽度與GPDH同工酶的分子類型與作用等等方面取得了一系列具有創新意義的研究成果。

  圍繞中藥中的藥食同源品種資源及其天然活性產物方面進行了多年研究,在國際著名期刊發表了大量學術論文。近期應Mini Reviews in Medicinal Chemistry邀請,提出了一期專刊的主題:本草組學(herbalomics),擔任該專輯的主編,該專刊將于2012年秋季出版,預期將會對中藥的國際化起到積極作用。
  所帶的研究生獲得過學校和學院設立的所有獎勵,包括教育部學術新人、學校優秀博士論文創新基金、各類企業獎學金、南粵優秀研究生,學校優秀研究生,學校十大學術新星等各類獎勵榮譽稱號。
  
  四、主要論文
  以下為近五年發表的SCI論文,均為通訊作者。
  
  2011年
  1.Chen, H., Lao, Y.M., Liu, G.N., Jiang, J.G. Effects of salinities on the gene expression of a (NAD+)- dependent glycerol-3-phosphate dehydrogenase in Dunaliella salina. Science of the Total Environment, 2011, 409 (7): 1291–1297. (IF 3.190)
  2.Tang, W.Q., Li, D.C., Lv, Y.X., Jiang, J.G. Concentration and drying of tea polyphenol extracted from green tea using molecular distillation and spray drying. Drying Technology, 2011, 29(5): 584–590. (IF 1.662)
  3.Qv, X.Y., Zeng, Z.P., Jiang, J.G. Preparation of lutein microencapsulation by complex coacervation method and its physicochemical properties and stability. Food Hydrocolloids, 2011, 25(6): 1596-1603. (IF 2.659)
  4.Ye, Z. W., Liu, G.N., Jiang, J. G. Structural and phylogenetic analysis of a novel ζ-carotene desaturase from Dunaliella bardawil, a β-carotene highly accumulated unicellular alga. Limnology and Oceanography, 2011, 56(1): 133-138. (IF 3.385)
  5.Xiao, K.J., Zhong, X.K., Wang, J., Jiang, J.G. Extraction of brown pigment from Rosa laevigata Michx and its antioxidant activity. Pharmaceutical Biology, 2011, 49(7):734-740. (IF 0.638)
  6.Chen, H., Jiang, J.G. Toxic effects of chemical pesticides (trichlorfon and dimehypo) on Dunaliella salina. Chemosphere, 2011, 84 (5): 664–670. (IF 3.155)
  7.Lao, Y.M., Ye, Z.W., Jiang, J.G., Zhou, S.S. In silico analysis of phytoene synthase and its promoter reveals hints for regulation mechanisms of carotenogenesis in Duanliella bardawil. Bioinformatics, 2011, 27(16): 2201-2208. (IF 4.877)
  8.Jiang, M.H., Yang, L., Jiang, J.G. Comparative GC\MS analysis of essential oil components extracted by three methods from the flower of Citrus aurantium L. var. amara Engl. Journal of Food Science (in print, IF 1.733)
  9.Lu, C.L., Zhu, L., Piao, J.H., Jiang, J.G. Chemical compositions extracted from Wikstroemia indica and their multiple activities. Pharmaceutical Biology, DOI: 10.3109/13880209.2011.596207, (in print, IF 0.638)
  10.Lv, W., Piao, J.H., Jiang, J.G. Typical toxic components in Chinese medicine and their toxicology. Expert Opinion on Drug Metabolism & Toxicology, (in revision, IF 3.374)
  11.Lu, Q., Li, D.C., Jiang, J.G. Preparation and physicochemical properties of tea polyphenol liposome. Journal of Agricultural and Food Chemistry, (in revision, IF 2.816)
  12.Lu, Q., Jiang, J.G. Chemical metabolism of active compounds from natural botanicals. Current Medicinal Chemistry, (in revision, IF 4.630)
  
  2010年
  13.Ye, Z. W., Wu, X. M., Jiang, J. G. Knockdown of angiotensinogen by shRNA-mediated RNA interference inhibit human visceral preadipocytes differentiation. International Journal of Obesity, 2010, 34(1): 157-164. (IF 5.125)
  14.Jiang, J. G., Zhu, Y. H. Preliminary and Comparative cultivations of D. salina in the photobioreactor with outdoors. Journal of Food Process Engineering, 2010, 33 (1): 104–114. (IF 0.875)
  15.Zeng, Z.P., Jiang, J.G. Analysis of the adverse reactions induced by natural product derived drugs. British Journal of Pharmacology. 2010, 159(7) 1374-1391. (IF 4.925)
  16.Tang, W.Q., Li, D.C., Lv, Y.X., Jiang, J.G. Extraction and removal of caffeine from green tea by ultrasonic-enhanced supercritical fluid. Journal of Food Science, 2010, 75(4): C363-C368. (IF 1.733)
  17.Yang, L., Cao, Y.L., Jiang, J.G., Lin, Q.S., Chen, J., Zhu, L. Response surface optimization of ultrasound-assisted flavonoids extraction from the flower of Citrus aurantium L. var. amara Engl. Journal of Separation Science, 2010, 33(9): 1349-1355. (IF 2.631)
  18.Zhong, X.K, Jin, X., Lai, F.Y., Lin, Q.S., Jiang, J.G. Chemical analysis and antioxidant activities in vitro of polysaccharide extracted from Opuntia ?cus indica Mill. cultivated in China. Carbohydrate Polymers, 2010, 82(3): 722-727. (IF 3.463)
  19.Ye, Z. W., Jiang, J. G. Analysis of an essential carotenogenic enzyme: ζ-carotene desaturase from unicellular alga Dunaliella salina. Journal of Agricultural and Food Chemistry, 2010, 58 (21): 11477–11482. (IF 2.816)
  20.Lu, C.L., Li, Y.M., Yang, L., Jiang, J.G., Lin, Q.S, Chen, J., Zhu, L. Extraction optimization of daphnoretin from root bark of Wikstroemia indica (L.) C. A. and its anti-tumor activity tests. Food Chemistry, 2011, 124(4): 1500-1506. (IF 3.458)
  21.Jiang, M.H., Zhu, L., Jiang, J.G. Immunoregulatory actions of polysaccharides from Chinese herbal medicine. Expert Opinion On Therapeutic Targets, 2010, 14(12): 1367-1402. (IF 3.649)
  22.Li, D.C., Jiang, J.G. Optimization of the microwave-assisted extraction conditions of tea phenols from green tea. International Journal of Food Sciences and Nutrition. 2010, 61(8): 837–845. (IF 0.778)
  23.Lu, C.L., Qv, X.Y, Jiang, J.G. Proteomics and syndromes of Chinese medicine. Journal of Cellular and Molecular Medicine. 2010 14(12): 2721–2728. (IF 4.608)
  24.Qv, X.Y., Jiang, J.G., Piao, J.H. Pharmacodynamic studies of Chinese medicine at whole animal, cell and molecular levels. Current Medicinal Chemistry, 2010, 17(36), 4521-4537. (IF 4.630)

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